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IP3R-I Polyclonal Antibody, 100ul[BT-AP04603] Dry Bath Expression studies indicate that this

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IP3R-I Polyclonal Antibody, 100ul[BT-AP04603] Dry Bath Expression studies indicate that thisITPR1 (inositol 1,4,5 trisphosphate receptor type 1) encodes an intracellular receptor for inositol 1,4,5 trisphosphate. Upon stimulation by inositol 1,4,5 trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in ITPR1 cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for ITPR1.

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Description

Expression studies indicate that this gene may have a potential role in tumorigenesis as an immortalizing agent

kidney and pancreas

Expressed predominantly in the brain

NBPF5 (neuroblastoma breakpoint family member 5) is a 351 amino acid cytoplasmic protein that is expressed in medulla and brain and belongs to the NBPF family

the gene for the other resides on chromosome 16

IP3R-I Polyclonal Antibody, 100ul[BT-AP04603] Dry Bath Expression studies indicate that thisITPR1 (inositol 1,4,5 trisphosphate receptor type 1) encodes an intracellular receptor for inositol 1,4,5 trisphosphate. Upon stimulation by inositol 1,4,5 trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in ITPR1 cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for ITPR1.

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