Nibrin Polyclonal Antibody, 20ul[BT-AP06022] Centrifugal Filter CHRNA1 encodes an alpha subunit

CHRNA1 encodes an alpha subunit that plays a role in acetlycholine binding/channel gating

as well as in the regulation of water excretion and cardiovascular functions

COP9 signalosome complex subunit 5 encoded by COPS5 is one of the eight subunits of COP9 signalosome

but their full-length natures have not been determined

MLH3 is a member of the MutL-homolog (MLH) family of DNA mismatch repair (MMR) genes

Nibrin Polyclonal Antibody, 20ul[BT-AP06022] Centrifugal Filter CHRNA1 encodes an alpha subunitMutations in NBN are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. Nibrin is a member of the MRE11 RAD50 double strand break repair complex which consists of 5 proteins. NBN product is thought to be involved in DNA double strand break repair and DNA damage induced checkpoint activation.