SIA8B Polyclonal Antibody, 100ul Antibody Humanization A similar protein in budding

A similar protein in budding yeast is a component of pre-60S ribosomal particles| and is required for the early maturation steps of the 60S subunit

Mutations in this gene have been associated with individuals affected by severe intellectual disability| early-onset epilepsy| microcephaly| congenital cataracts| growth retardation| and spasticity (PMID: 25439727)

The protein is associated with secretory granules and modulates synaptic transmission and synaptic plasticity

TORC2 does not bind to and is not sensitive to FKBP12-rapamycin

Knockout studies in mice suggest that this subunit may play an important role in regulating energy balance and adiposity

SIA8B Polyclonal Antibody, 100ul Antibody Humanization A similar protein in buddingThe protein encoded by this gene is a type II membrane protein that is thought to catalyze the transfer of sialic acid from CMP sialic acid to N linked oligosaccharides and glycoproteins. The encoded protein may be found in the Golgi apparatus and may be involved in the production of polysialic acid, a modulator of the adhesive properties of neural cell adhesion molecule (NCAM1). This protein is a member of glycosyltransferase family 29.