PAK gamma(Phospho Ser197) Polyclonal Antibody, 50ul Long RNA Synthesis Significant expression of this protein

Significant expression of this protein has been observed in the placenta

|tissue specificity:Synthesized in liver and selectively concentrated in bone matrix

This isozyme is also a selenoprotein| containing the rare amino acid selenocysteine (Sec) at its active site

Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis

Mutations in this gene are associated with platelet-type bleeding disorders| which are characterized by a failure of platelet aggregation| including Glanzmann thrombasthenia

PAK gamma(Phospho Ser197) Polyclonal Antibody, 50ul Long RNA Synthesis Significant expression of this proteinThe p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase mediated apoptosis, and may play a role