KDEL Receptor 3 Polyclonal Antibody, 50ul Dialysis type I(IL1R1/IL1RA)

type I(IL1R1/IL1RA)

The protein may play a role in repression of interleukin-2 and matrix metalloproteinase-1 transcription

Loss of function or expression of this gene has been detected in multiple tumors

Matrix metallopeptidase 15 may play a role in cancer progression

Binding occurs as a ternary complex of methionyl-tRNA

KDEL Receptor 3 Polyclonal Antibody, 50ul Dialysis type I(IL1R1/IL1RA)KDELR3 encodes a member of the KDEL endoplasmic reticulum protein retention receptor family. Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis Golgi, or a pre Golgi compartment. Sorting of these proteins is dependent on a C terminal tetrapeptide signal, usually lys asp glu leu (KDEL) in animal cells, and his asp glu leu (HDEL) in S.