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RFOX1 Polyclonal Antibody, 50ul Buffer Solutions The encoded protein shares a

SKU: 75679766099

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RFOX1 Polyclonal Antibody, 50ul Buffer Solutions The encoded protein shares aThe Fox 1 family of RNA binding proteins is evolutionarily conserved, and regulates tissue specific alternative splicing in metazoa. Fox 1 recognizes a (U)GCAUG stretch in regulated exons or in flanking introns. The protein binds to the C terminus of ataxin 2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin 2 is the product of the SCA2 gene which causes familial neurodegenerative diseases. Fox 1 and ataxin

Store: gaabil.dk · Domain: gaabil.dk

Description

The encoded protein shares a high level of similarity to the rat homolog| and contains 3 C2 domains and a diacylglycerol-binding C1 domain

It functions as a chemoattractant

Contains 9 ANK repeats

but is actually an apelin receptor that inhibits adenylate cyclase activity and plays a counter-regulatory role against the pressure action of angiotensin II by exerting hypertensive effect

Promotes neuritogenesis in developing hippocampal neurons

RFOX1 Polyclonal Antibody, 50ul Buffer Solutions The encoded protein shares aThe Fox 1 family of RNA binding proteins is evolutionarily conserved, and regulates tissue specific alternative splicing in metazoa. Fox 1 recognizes a (U)GCAUG stretch in regulated exons or in flanking introns. The protein binds to the C terminus of ataxin 2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin 2 is the product of the SCA2 gene which causes familial neurodegenerative diseases. Fox 1 and ataxin

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