HLAG Polyclonal Antibody, 100ul Bottle-Top Dispenser Mutations in this gene have

Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia

It encodes one of the seven mammalian TRPC (transient receptor potential channel) proteins

Ran binds to the importin

May play a role in changing or maintaining the spatial distribution of cytoskeletal structures (By similarity)

and colon cancers

HLAG Polyclonal Antibody, 100ul Bottle-Top Dispenser Mutations in this gene haveHLA G belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta 2 microglobulin). The heavy chain is anchored in the membrane. HLA G is expressed on fetal derived placental cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide,