Bcl-2 Polyclonal Antibody, 100ul[BT-AP00857] Sealing Film Family members are well conserved

Family members are well conserved in their genomic (number and size of exons) and protein (aa length among species) structures yet have markedly different tissue expression patterns

Mutations in Nkx2-6 are associated with persistent truncus arteriosus

Long-term LPS infusion finally increases expression of the membrane-bound form on circulating monocytes

including SLITRK5

Interacts with DNTTIP2| FAM120B and UIMC1

Bcl-2 Polyclonal Antibody, 100ul[BT-AP00857] Sealing Film Family members are well conservedBCL2 encodes an integral outer mitochondrial membrane protein (BCL2, apoptosis regulator) that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants.