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DARPP-32(Phospho Thr34) Polyclonal Antibody, 100ul Lysosome meningocerebrovascular amyloidosis

SKU: 74858823342

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DARPP-32(Phospho Thr34) Polyclonal Antibody, 100ul Lysosome meningocerebrovascular amyloidosisThis gene encodes a bifunctional signal transduction molecule. Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor. As a target for dopamine, this gene may serve as a therapeutic target for neurologic and psychiatric disorders. Multiple transcript variants encoding different isoforms have been found for this gene.

Store: gaabil.dk · Domain: gaabil.dk

Description

meningocerebrovascular amyloidosis

The encoded protein is localized mainly in the cytoplasm| with some in the mitochondria| suggesting that it is involved in the sanitization of nucleotide pools both for nuclear and mitochondrial genomes

The encoded protein is a type I PRMT and is responsible for the majority of cellular arginine methylation activity

Alternative splicing results in multiple transcript variants

active enzyme is produced following lipopolysaccharide expression in mature dendritic cells

DARPP-32(Phospho Thr34) Polyclonal Antibody, 100ul Lysosome meningocerebrovascular amyloidosisThis gene encodes a bifunctional signal transduction molecule. Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor. As a target for dopamine, this gene may serve as a therapeutic target for neurologic and psychiatric disorders. Multiple transcript variants encoding different isoforms have been found for this gene.

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