ROBO4 Polyclonal Antibody, 100ul High Speed Micro-Centrifuges Defects in this gene are

Defects in this gene are associated with Fuchs endothelial corneal dystrophy and posterior polymorphous corneal dystrophy type 2

The SERPINA1 gene is also located on chromosome 14 and

or overexpressed in several kinds of cancers

Expression of a kinase-defective mutant results in abnormal cell morphology caused by changes in microtubule dynamics and mitotic arrest followed by apoptosis

The protein encoded by PLN (phospholamban) is found as a pentamer and is a major substrate for the cAMP-dependent protein kinase in cardiac muscle

ROBO4 Polyclonal Antibody, 100ul High Speed Micro-Centrifuges Defects in this gene areReceptor for Slit proteins, at least for SLIT2, and seems to be involved in angiogenesis and vascular patterning. May mediate the inhibition of primary endothelial cell migration by Slit proteins.,Belongs to the immunoglobulin superfamily. ROBO family.,Contains 2 fibronectin type III domains.,Contains 2 Ig like C2 type (immunoglobulin like) domains.,subunit: Interacts with SLIT2 and ENAH.,tissue specificity: Specifically expressed in endothelial