RASL2 Polyclonal Antibody, 20ul Liquid Handling ＆Storage Mediator complex subunit 17 encoded

Mediator complex subunit 17 encoded by MED17 is a subunit of the CRSP (cofactor required for SP1 activation) complex

PPARG and RARA

It is essential for the translation repression activity of the protein

specifically reacting with the simian virus 40 tumor antigen

This locus was originally described as a pseudogene

RASL2 Polyclonal Antibody, 20ul Liquid Handling ＆Storage Mediator complex subunit 17 encodedThis gene encodes a member of the GAP1 family of GTPase activating proteins that suppresses the Ras mitogen activated protein kinase pathway in response to Ca(2+). Stimuli that increase intracellular Ca(2+) levels result in the translocation of this protein to the plasma membrane, where it activates Ras GTPase activity. Consequently, Ras is converted from the active GTP bound state to the inactive GDP bound state and no longer activates downstream