Raf-1 Polyclonal Antibody, 50ul[BT-AP13534] Cell Function Analysis Deficiencies in this gene can

Deficiencies in this gene can result in male pseudohermaphroditism

This gene encodes an enzyme involved in the first step of glycosylphosphatidylinositol (GPI)-anchor biosynthesis

NF-kappa-B inhibitor alpha interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses

the powerful enzyme with 20 Units/μL activity in a compact 1 mL package

It forms a 1-to-1 noncovalent complex with glycoprotein Ib

Raf-1 Polyclonal Antibody, 50ul[BT-AP13534] Cell Function Analysis Deficiencies in this gene canThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.