UN45A Rabbit Polyclonal Antibody, 50ul Dry Bath In vitro studies have shown

In vitro studies have shown a 10- to 15-fold increase in the kinase activity of Lck bound to CD5

Mutations in this gene have been associated with Niemann-Pick disease| type C2 and frontal lobe atrophy

Antibodies to the encoded protein were found in some patients with neurologic symptoms who had paraneoplastic syndrome

The MAD proteins compete for MAX binding with MYC

suggesting a role in tumor development and metastasis

UN45A Rabbit Polyclonal Antibody, 50ul Dry Bath In vitro studies have shownUNC45A plays a role in cell proliferation and myoblast fusion binds progesterone receptor (PGR; MIM 607311) and HSP90 (HSPCA; MIM 140571) and acts as a regulator of the progesterone receptor chaperoning pathway (Price et al. 2002