PRP6 Polyclonal Antibody, 50ul Recombinant Protein Mutations in this gene cause

Mutations in this gene cause autosomal-recessive intellectual disability

Both INSIG1 protein and this protein are endoplasmic reticulum proteins that block the processing of sterol regulatory element binding proteins (SREBPs) by binding to SREBP cleavage-activating protein (SCAP)

with a concentration of 175KU/mL

which is necessary for their anti-apoptotic function

Aberrant expression of this gene is associated with cancer progression in multiple tissues

PRP6 Polyclonal Antibody, 50ul Recombinant Protein Mutations in this gene causeThe pre mRNA processing factor 6 encoded by PRPF6 appears to be involved in pre mRNA splicing, possibly acting as a bridging factor between U5 and U4 U6 snRNPs in formation of the spliceosome. The encoded protein also can bind androgen receptor, providing a link between transcriptional activation and splicing.