PARP8 Polyclonal Antibody, 20ul Gloves This gene and two other

This gene and two other related trefoil family member genes are found in a cluster on chromosome 21

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autosomal dominant or X-linked inheritance

An important paralog of this gene is MID1

The encoded protein is also a candidate tumor suppressor protein| and aberrant promoter methylation of this gene may play a role in cervical cancer

PARP8 Polyclonal Antibody, 20ul Gloves This gene and two otherCatalytic activity: NAD(+) + (ADP D ribosyl)(n) acceptor = nicotinamide + (ADP D ribosyl)(n+1) acceptor.,PTM: Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence Contaminating sequence. Potential poly A sequence.,Contains 1 PARP catalytic domain.,