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UVRAG Polyclonal Antibody, 20ul Pathway and Network Analysis This gene is a protooncogene

SKU: 72919613443

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UVRAG Polyclonal Antibody, 20ul Pathway and Network Analysis This gene is a protooncogeneThis gene complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1 PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left right axis malformation and mutations in this gene have been associated with colon cancer.

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Description

This gene is a protooncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes| including cell division| adhesion| differentiation| and response to stress

This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component

and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells

This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains

which binds to one of the components of the multiprotein editosome complex

UVRAG Polyclonal Antibody, 20ul Pathway and Network Analysis This gene is a protooncogeneThis gene complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1 PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left right axis malformation and mutations in this gene have been associated with colon cancer.

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