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DNA pol Gamma2 Polyclonal Antibody, 50ul Microbial Genome Editing and expression of ERGIC3 was

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DNA pol Gamma2 Polyclonal Antibody, 50ul Microbial Genome Editing and expression of ERGIC3 wasPOLG2 encodes the processivity subunit of the mitochondrial DNA polymerase gamma. The DNA polymerase gamma 2, accessory subunit forms a heterotrimer containing one catalytic subunit and two processivity subunits. This protein enhances DNA binding and promotes processive DNA synthesis. Mutations in this gene result in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions.

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Description

and expression of ERGIC3 was correlated with the differentiated degree and histological type of lung cancer (PMID: 23374247)

ERK1/2 and MAPK14/p38-alpha may play a role in this process

The gene is expressed in most nonlymphoid human tissues including prostate

It is heterogeneously expressed in the brain

The protein encoded by this gene functions as a receptor or| with Frizzled| a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade

DNA pol Gamma2 Polyclonal Antibody, 50ul Microbial Genome Editing and expression of ERGIC3 wasPOLG2 encodes the processivity subunit of the mitochondrial DNA polymerase gamma. The DNA polymerase gamma 2, accessory subunit forms a heterotrimer containing one catalytic subunit and two processivity subunits. This protein enhances DNA binding and promotes processive DNA synthesis. Mutations in this gene result in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions.

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