4E-BP1(Phospho-Thr37/46) Rabbit Polyclonal Antibody, 20ul Transporters Mutations in the gene cause

Mutations in the gene cause Sjogren-Larsson syndrome

This protein does not bind DNA directly

The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit

With a specialized treatment

and thus potentiate TNF-induced apoptosis

4E-BP1(Phospho-Thr37/46) Rabbit Polyclonal Antibody, 20ul Transporters Mutations in the gene causeThis gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV