NTN Polyclonal Antibody, 100ul Buffer Solutions This protein may be involved

This protein may be involved in tumor suppression

is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure

This protein may also be a potential biomarker for certain tumors

Defects in EP300 are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer

with the SV40 large T-antigen binding only to the unphosphorylated form of each protein

NTN Polyclonal Antibody, 100ul Buffer Solutions This protein may be involvedNRTN encodes a secreted ligand of the TGF beta (transforming growth factor beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein. Neurturin signals through the RET receptor tyrosine kinase and a GPI linked coreceptor, and promotes survival of neuronal populations. A neurturin mutation has been described in a family with Hirschsprung Disease.