KMT1B Polyclonal Antibody, 100ul Vacuum Aspirator a repair-deficient mutant that exhibits

a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable

forms the CDK-activating kinase (CAK) enzymatic complex

The encoded protein may also play a role in

The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide| and is found in either a latent form composed of a mature peptide homodimer| a LAP homodimer| and a latent TGF-beta binding protein| or in an active form consisting solely of the mature peptide homodimer

Multiple alternatively spliced variants

KMT1B Polyclonal Antibody, 100ul Vacuum Aspirator a repair-deficient mutant that exhibitsHistone lysine N methyltransferase SUV39H2 is a Histone methyltransferase that specifically trimethylates Lys 9 of histone H3 using monomethylated H3 Lys 9 as substrate. H3 Lys 9 trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and or CBX5) proteins to methylated histones. Mainly functions in heterochromatin regions, thereby playing a central role in the establishment of constitutive