Phospho-Btk (Y223) Polyclonal Antibody, 100ul Organelle Studies Reciprocal translocations between chromosomes 22

Reciprocal translocations between chromosomes 22 and 17

S100 genes include at least 13 members which are located as a cluster on chromosome 1q21| however

WWOX (WW domain containing oxidoreductase) encodes a member of the short-chain dehydrogenases/reductases (SDR) protein family

The protein encoded by this gene is one of three related synaptic vesicle proteins

The Reg gene family is a multigene family grouped into four subclasses

Phospho-Btk (Y223) Polyclonal Antibody, 100ul Organelle Studies Reciprocal translocations between chromosomes 22Bruton tyrosine kinase encoded by BTK plays a crucial role in B cell development. Mutations in BTK cause X linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.