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PCDAA Rabbit Polyclonal Antibody, 50ul Cell Biology KDELR3 encodes a member of

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PCDAA Rabbit Polyclonal Antibody, 50ul Cell Biology KDELR3 encodes a member ofThis gene is a member of the protocadherin alpha gene cluster one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B cell and T cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N terminal

Store: gaabil.dk · Domain: gaabil.dk

Description

KDELR3 encodes a member of the KDEL endoplasmic reticulum protein retention receptor family

thus may function in signaling pathways utilized broadly during fetal development

It is strongly expressed in the cell lines of promyelocytic leukemia and Burkitt's lymphoma

suggesting that these proteins can escape the ER and recycle back

Defects in this gene are a cause of Fukuyama-type congenital muscular dystrophy (FCMD)

PCDAA Rabbit Polyclonal Antibody, 50ul Cell Biology KDELR3 encodes a member ofThis gene is a member of the protocadherin alpha gene cluster one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B cell and T cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N terminal

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