Akt1 Polyclonal Antibody, 50ul[BT-AP00340] Culture Plate Inserts The protein kinase domain is

The protein kinase domain is predicted to be catalytically inactive

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Molecular diagnosis involves using nucleic acids or proteins as biomarkers to help diagnose and treat diseases more effectively

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Expressed specifically in the hippocampus and Purkinje cells of the brain

Akt1 Polyclonal Antibody, 50ul[BT-AP00340] Culture Plate Inserts The protein kinase domain isThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a