Tuberin Polyclonal Antibody, 100ul[BT-AP09287] Peptide Library FOXO3 likely functions as a

FOXO3 likely functions as a trigger for apoptosis through expression of genes necessary for cell death

an event that can trigger a protein-protein interaction cascade which may ultimately effect gene expression and cellular function

An important paralog of this gene is LONP1

peripheral blood leukocyte

hereditary hemorrhagic telangiectasia and erythropoietic protoporphyria are associated with chromosome 18

Tuberin Polyclonal Antibody, 100ul[BT-AP09287] Peptide Library FOXO3 likely functions as aMutations in TSC2 lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.