DEF6 Polyclonal Antibody, 100ul Virus Packaging A mutation in this gene

A mutation in this gene was associated with mental retardation

The protein encoded by this gene is a member of the serpin (serine proteinase inhibitor) superfamily

May be involved in the sorting or targeting of critical proteins involved in the initiating events of endocytosis at the plasma membrane

This protein is also localized to the endoplasmic reticulum lumen

but the biological validity of some variants has not been determined

DEF6 Polyclonal Antibody, 100ul Virus Packaging A mutation in this geneDefensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes appear to be clustered on