INGR2 Polyclonal Antibody, 20ul Inoculating Loops/Needles This phosphoprotein is a transcriptional

This phosphoprotein is a transcriptional repressor and may play a role during cellular proliferation

encodes over 1

|PTM:Phosphorylated in the C-terminal upon stimulation by nerve growth factor (NGF) and epidermal growth factor (EGF)

It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system

and the ceramide metabolites sphingosine and sphingosine-1-phosphate (S1P) are important bioregulatory molecules

INGR2 Polyclonal Antibody, 20ul Inoculating Loops/Needles This phosphoprotein is a transcriptionalThis gene (IFNGR2) encodes the non ligand binding beta chain of the gamma interferon receptor. Human interferon gamma receptor is a heterodimer of IFNGR1 and IFNGR2. Defects in IFNGR2 are a cause of mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection. MSMD is a genetically heterogeneous disease with autosomal recessive, autosomal dominant or X linked inheritance.