Rat Angiopoietin 2, ANG-2 ELISA Kit, 96T Peptide Modification |Transcriptional activator

|Transcriptional activator

It belongs to the quinone oxidoreductase subfamily of zinc-containing alcohol dehydrogenase proteins

which mediates cell lysis

Promotes cell proliferation and neurogenesis in undifferentiated neural progenitor cells at the embryonic stage and inhibits differentiation of astrocytes (By similarity)

TOP2A encoding this enzyme functions as the target for several anticancer agents and a variety of mutations in this gene have been associated with the development of drug resistance

Rat Angiopoietin 2, ANG-2 ELISA Kit, 96T Peptide Modification |Transcriptional activatorBinds to TEK TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2 mediated loosening of cell matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a