Rag A/B Polyclonal Antibody, 20ul Filtration Alternative splicing of this PEG3

Alternative splicing of this PEG3 gene results in multiple transcript variants encoding distinct isoforms

Mutation in this gene has been associated with Naxos disease

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Mutations in ACTA1 cause nemaline myopathy type 3

Rag A/B Polyclonal Antibody, 20ul Filtration Alternative splicing of this PEG3Has guanine nucleotide binding activity but undetectable intrinsic GTPase activity. Required for the amino acid induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids. Involved in the RCC1 Ran GTPase pathway. May play a direct role in a TNF alpha signaling pathway leading to induction of cell death. May alternatively act as