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DAB2 Rabbit Polyclonal Antibody, 100ul Protein Post-translational Modification and being expressed in vascular

SKU: 7032490295

4.2
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DAB2 Rabbit Polyclonal Antibody, 100ul Protein Post-translational Modification and being expressed in vascularThis gene encodes a mitogen responsive phosphoprotein. It is expressed in normal ovarian epithelial cells but is down regulated or absent from ovarian carcinoma cell lines suggesting its role as a tumor suppressor. This protein binds to the SH3 domains of GRB2 an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras) via its C terminal proline rich sequences and may thus modulate growth factor Ras

Store: gaabil.dk · Domain: gaabil.dk

Description

and being expressed in vascular endothelium cells and binding to L-selectin

hypomethylation of the CAGE promoter region is associated with tumor progression and may serve as a valuable marker in cancer diagnosis

A pseudogene of this gene is located on the long arm of chromosome 7

They are differentially regulated after early development

This protein functions as a receptor for bile acids

DAB2 Rabbit Polyclonal Antibody, 100ul Protein Post-translational Modification and being expressed in vascularThis gene encodes a mitogen responsive phosphoprotein. It is expressed in normal ovarian epithelial cells but is down regulated or absent from ovarian carcinoma cell lines suggesting its role as a tumor suppressor. This protein binds to the SH3 domains of GRB2 an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras) via its C terminal proline rich sequences and may thus modulate growth factor Ras

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