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PTEN mouse Monoclonal Antibody(9E8), 100ul Liquid Handling &Storage This enzyme is thought to

SKU: 70298759732

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PTEN mouse Monoclonal Antibody(9E8), 100ul Liquid Handling &Storage This enzyme is thought toThis gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded by this gene is a phosphatidylinositol 3,4,5 trisphosphate 3 phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide

Store: gaabil.dk · Domain: gaabil.dk

Description

This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense

thus leading to cohesin dephosphorylation (By similarity)

This protein is overexpressed in epithelial mesotheliomas| ovarian cancers and in specific squamous cell carcinomas

|subunit:When phosphorylated| interacts directly with the PIK3R1 subunit of phosphoinositide 3-kinase and the SH2 domains of GRB2| GRAP| GRAP2| PLCG1 and PLCG2

Upon binding of thrombopoietin CD110 is dimerized and the JAK family of non-receptor tyrosine kinases

PTEN mouse Monoclonal Antibody(9E8), 100ul Liquid Handling &Storage This enzyme is thought toThis gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded by this gene is a phosphatidylinositol 3,4,5 trisphosphate 3 phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide

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