DGCR8 Rabbit Polyclonal Antibody, 50ul Drug Development and Evaluation This gene encodes a member

This gene encodes a member of the mutS family of proteins that are involved in DNA mismatch repair and meiotic recombination

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The protein forms homo-oligomers via the coilel-coil region and localizes to cytoplasmic bodies

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an alternative non-homologous end-joining (NHEJ) machinery triggered in response to double-strand breaks in DNA (PubMed: 25642963

DGCR8 Rabbit Polyclonal Antibody, 50ul Drug Development and Evaluation This gene encodes a memberThis gene encodes a subunit of the microprocessor complex which mediates the biogenesis of microRNAs from the primary microRNA transcript. The encoded protein is a double stranded RNA binding protein that functions as the non catalytic subunit of the microprocessor complex. This protein is required for binding the double stranded RNA substrate and facilitates cleavage of the RNA by the ribonuclease III protein Drosha. Alternate splicing results in