PLEK2 Rabbit Polyclonal Antibody, 100ul Roller Bottles Mutations in PRKAR1A cause Carney

Mutations in PRKAR1A cause Carney complex (CNC)

Each bottle contains 50 L of solution

The gene encoding CLIP4 maps to human chromosome 2p23

Also component of the mSin3A complex which acts to repress transcription by deacetylation of nucleosomal histones

An important paralog of this gene is GPR179

PLEK2 Rabbit Polyclonal Antibody, 100ul Roller Bottles Mutations in PRKAR1A cause CarneyThe protein encoded by this gene associates with membrane bound phosphatidylinositols generated by phosphatidylinositol 3 kinase. The encoded protein then interacts with the actin cytoskeleton to induce cell spreading. In conjunction with complement component 1 q subcomponent B chain (C1QB) this gene shows an increase in expression in melanoma cells and may serve as an accurate biomarker for the disease.