Saposin Polyclonal Antibody, 50ul Vacuum Aspirator Two transcript variants encoding different

Two transcript variants encoding different isoforms have been found for CDC25A

Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype

|subcellular location:Generally located in the nucleoplasm

elongins B and C

strong ectopic expression has been detected in ovarian adenocarcinoma

Saposin Polyclonal Antibody, 50ul Vacuum Aspirator Two transcript variants encoding differentPSAP (prosaposin) encodes a highly conserved preproprotein that is proteolytically processed to generate four main cleavage products including saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with