CAD12 Polyclonal Antibody, 20ul Human Genome Knockout Libraries Mutations in this gene have

Mutations in this gene have been associated with insulin-dependent diabetes mellitus

LH is expressed in the pituitary gland and promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids

Humans have multiple pseudogenes of this gene

studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis

tissue specificity:High expression in spinal cord and moderate expression in all other tissues and specific brain regions examined

CAD12 Polyclonal Antibody, 20ul Human Genome Knockout Libraries Mutations in this gene haveThis gene encodes a type II classical cadherin of the cadherin superfamily. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature cadherin protein. These integral membrane proteins mediate calcium dependent cell cell adhesion and are composed of a large N terminal extracellular domain, a single membrane spanning domain,