IKK gamma Polyclonal Antibody, 50ul[BT-AP02164] Peptide Library a mitochondrial inner membrane Ca2+

a mitochondrial inner membrane Ca2+ channel

Defects in this gene have been reported to cause spastic paraplegia autosomal dominant type 42 (SPG42) in one Chinese family| but not in similar patients of European descent

and adenocarcinoma of lung

Origin recognition complex subunit 1 contains an OTU domain and binds Ubal (ubiquitin aldehyde)

The protein may also be involved in cardiac physiology and may be associated with the pathogenesis of atrial fibrillation

IKK gamma Polyclonal Antibody, 50ul[BT-AP02164] Peptide Library a mitochondrial inner membrane Ca2+This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex which activates NF kappaB resulting in activation of genes involved in inflammation immunity cell survival and other pathways. Mutations in this gene result in incontinentia pigmenti hypohidrotic ectodermal dysplasia and several other types of immunodeficiencies. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome.