FBXW2 Rabbit Polyclonal Antibody, 50ul Enzymes & Activity Assays Many alternatively spliced transcript variants

Many alternatively spliced transcript variants

this protein is essential for the regulation of precursor cell proliferation and the control of neuronal differentiation and migration during hippocampal development

This gene encodes a protein that catalyzes the synthesis of 2-hydroxysphingolipids

In conjuction with other heat shock proteins

and can function as a bimodal regulator of epidermal growth factor receptor/mitogen-activated protein kinase signaling

FBXW2 Rabbit Polyclonal Antibody, 50ul Enzymes & Activity Assays Many alternatively spliced transcript variantsF box proteins are an expanding family of eukaryotic proteins characterized by an approximately 40 amino acid motif the F box. Some F box proteins have been shown to be critical for the ubiquitin mediated degradation of cellular regulatory proteins. In fact F box proteins are one of the four subunits of ubiquitin protein ligases called SCFs. SCF ligases bring ubiquitin conjugating enzymes to substrates that are specifically recruited by the different