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TFPI Polyclonal Antibody, 100ul Pipette Micro Tips VCP and NPLOC4 binds ubiquitinated

SKU: 68763176459

4.3
PLN141.00 PLN161.00

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TFPI Polyclonal Antibody, 100ul Pipette Micro Tips VCP and NPLOC4 binds ubiquitinatedTFPI encodes a Kunitz type serine protease inhibitor that regulates the tissue factor (TF) dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa TF proteases in an autoregulatory loop.

Store: gaabil.dk · Domain: gaabil.dk

Description

VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm

|miscellaneous:Engagement of killer inhibitory receptors (KIR) disrupts the interaction of PLCG1 with LAT and blocks target cell-induced activation of PLC| maybe by inducing the dephosphorylation of LAT

GTP-binding proteins

PMID: 15805470)

due to the N-terminal 1-49 amino acid sequence that could be cut down

TFPI Polyclonal Antibody, 100ul Pipette Micro Tips VCP and NPLOC4 binds ubiquitinatedTFPI encodes a Kunitz type serine protease inhibitor that regulates the tissue factor (TF) dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa TF proteases in an autoregulatory loop.

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