PCSK9 Rabbit Polyclonal Antibody, 50ul[BT-AP11847] Bottle-Top Dispenser Mutations in this gene are

Mutations in this gene are associated with methylmalonic aciduria

which mediates interaction with transcriptional coactivators and ligand-bound nuclear receptors

Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene

It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif

Alternatively spliced transcript variants encoding distinct isoforms have been reported

PCSK9 Rabbit Polyclonal Antibody, 50ul[BT-AP11847] Bottle-Top Dispenser Mutations in this gene areProprotein convertase subtilisin kexin type 9 (PCSK9) is an enzyme encoded by the PCSK9 gene in humans on chromosome 1. It is the 9th member of the proprotein convertase family of proteins that activate other proteins. Similar genes (orthologs) are found across many species. As with many proteins, PCSK9 is inactive when first synthesized, because a section of peptide chains blocks their activity; proprotein convertases remove that section to activate