IBTK Polyclonal Antibody, 100ul Cell Culture & Maintenance PAK family members are known

PAK family members are known to be effectors of Rac/Cdc42 GTPases

MOB kinase activator 3C encoded by MOB3C is similar to the yeast Mob1 protein

but another polymorphism has been associated with increased plasma cholesterol levels

Elevated expression of this gene has been observed in oral squamous cell carcinoma

This protease regulates SUMO pathways by deconjugating sumoylated proteins

IBTK Polyclonal Antibody, 100ul Cell Culture & Maintenance PAK family members are knownBruton tyrosine kinase (BTK) is a protein tyrosine kinase that is expressed in B cells, macrophages, and neutrophils. The protein encoded by this gene binds to BTK and downregulates BTK's kinase activity. In addition, the encoded protein disrupts BTK mediated calcium mobilization and negatively regulates the activation of nuclear factor kappa B driven transcription. This gene has a pseudogene on chromosome 18. Alternative splicing results in multiple