PAR-6Beta Polyclonal Antibody, 50ul Pathway and Network Analysis ARID4B encodes a protein with

ARID4B encodes a protein with sequence similarity to retinoblastoma-binding protein-1

Plays a key role in the antiproliferative action of IFN-gamma either by inhibiting the ERK activition or by arresting cell growth in G1 phase in a p53-dependent manner

The encoded protein acts on the protein phosphatase-2A catalytic subunit and supports the ERK pathway through dephosphorylation of regulatory proteins

This suggests that BTBD6 may play a role in transcription regulation in the lens

|Contains 1 BAR domain

PAR-6Beta Polyclonal Antibody, 50ul Pathway and Network Analysis ARID4B encodes a protein withPARD6B is a member of the PAR6 family and encodes a protein with a PSD95 Discs large ZO1 (PDZ) domain, an OPR domain and a semi Cdc42 Rac interactive binding (CRIB) domain. This cytoplasmic protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi protein complex.