NMRL1 Rabbit Polyclonal Antibody, 20ul Immunology also known as Lon protease

also known as Lon protease

The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks

This protein can interact with the cytoplasmic domain of the ErbB3 receptor and may contribute to transducing growth regulatory signals

Mutations in this gene are associated with Rothmund-Thomson

It may also regulate cell growth during dendritic cell or B cell activation and development

NMRL1 Rabbit Polyclonal Antibody, 20ul Immunology also known as Lon proteaseThis gene encodes an NADPH sensor protein that preferentially binds to NADPH. The encoded protein also negatively regulates the activity of NF kappaB in a ubiquitylation dependent manner. It plays a key role in cellular antiviral response by negatively regulating the interferon response factor 3 mediated expression of interferon beta. Alternative splicing of this gene results in multiple transcript variants.