DNJC3 Polyclonal Antibody, 20ul Centrifuges Disease-associated mutations tend to be

Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product

both of which are the potent inducers of cell apoptosis

These proteins modulate many physiological processes

Related pseudogenes exist on chromosomes 2 and X

DCK is clinically important because of its relationship to drug resistance and sensitivity

DNJC3 Polyclonal Antibody, 20ul Centrifuges Disease-associated mutations tend to beThis gene encodes a protein with multiple tetratricopeptide repeat (TPR) motifs as well as the highly conserved J domain found in DNAJ chaperone family members. It is a member of the tetratricopeptide repeat family of proteins and acts as an inhibitor of the interferon induced, dsRNA activated protein kinase (PKR).