Rat Nephrin, NPHN ELISA Kit, 96T Yeast Expression cleaves SPHK2 which is released

cleaves SPHK2 which is released from cells and remains enzymatically active extracellularly

minimizing errors and improving data repeatability

Allelic variants of this gene are associated with generalized epilepsy with febrile seizures and epileptic encephalopathy

Component of RNA polymerase I which synthesizes ribosomal RNA precursors

It also plays a role in nuclear pre-mRNA retention and transcriptional repression

Rat Nephrin, NPHN ELISA Kit, 96T Yeast Expression cleaves SPHK2 which is releasedSeems to play a role in the development or function of the kidney glomerular filtration barrier. Regulates glomerular vascular permeability. May anchor the podocyte slit diaphragm to the actin cytoskeleton. Plays a role in skeletal muscle formation through regulation of myoblast fusion.