S5A2 Polyclonal Antibody, 100ul Antibody Humanization miscellaneous:'Reprimo' signifies stop/repress

miscellaneous:'Reprimo' signifies stop/repress

Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized

Mutations in this gene result in colobomata

leucine zipper (bZIP) transcription factor belonging to the Jun family that includes c-Jun and JunD

Alternatively spliced transcript variants encoding multiple isoforms have been observed for DHPS

S5A2 Polyclonal Antibody, 100ul Antibody Humanization miscellaneous:'Reprimo' signifies stop/repressThis gene encodes a microsomal protein expressed at high levels in androgen sensitive tissues such as the prostate. The encoded protein is active at acidic pH and is sensitive to the 4 azasteroid inhibitor finasteride. Deficiencies in this gene can result in male pseudohermaphroditism, specifically pseudovaginal perineoscrotal hypospadias (PPSH).