Smad3 mouse Monoclonal Antibody(4C9), 100ul Cell Culture and multiple phosphorylation sites and

and multiple phosphorylation sites and glutamic acid/proline (EP) repeats at the C-terminal region

Mutations in this gene have been associated with Tangier's disease and familial high-density lipoprotein deficiency

It is expressed in fetal and adult brain as well as in several other organs such as the lung and gut

Additional isoforms produced by alternative splicing seem to exist

and is necessary for the expression of glucose transporter

Smad3 mouse Monoclonal Antibody(4C9), 100ul Cell Culture and multiple phosphorylation sites andThe protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor beta and is thought to play a role in the regulation of