Na+ CP type IX Alpha Polyclonal Antibody, 100ul Bottles Mutations in this gene have

Mutations in this gene have been found in individuals with autosomal dominant mental retardation

function:Component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and

The encoded protein is activated by bone morphogenetic proteins type 1 receptor kinase

and adenocarcinoma of lung

The gene is located near the Smith-Magenis syndrome region on chromosome 17

Na+ CP type IX Alpha Polyclonal Antibody, 100ul Bottles Mutations in this gene haveSCN9A encodes a voltage gated sodium channel which plays a significant role in nociception signaling. Mutations in SCN9A have been associated with primary erythermalgia, channelopathy associated insensitivity to pain, and paroxysmal extreme pain disorder.