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LKB1(Phospho Ser428) Polyclonal Antibody, 100ul Antibody Humanization with other brain malformations 6

SKU: 66603297735

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LKB1(Phospho Ser428) Polyclonal Antibody, 100ul Antibody Humanization with other brain malformations 6This gene, which encodes a member of the serine threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in this gene have been associated with Peutz Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of this gene have been observed but have not

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Description

with other brain malformations 6

and glycogen synthase kinase-3 (GSK-3) signaling pathways

with normal or slightly elevated thyroid stimulating hormone (TSH)

This gene belongs to the more telomeric copy of the duplicated region

Disruption of this gene in mice resulted in abnormal embryonic blood vessel formation

LKB1(Phospho Ser428) Polyclonal Antibody, 100ul Antibody Humanization with other brain malformations 6This gene, which encodes a member of the serine threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in this gene have been associated with Peutz Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of this gene have been observed but have not

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