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SMG9 Polyclonal Antibody, 100ul Isothermal Amplification Acts as a nucleolar anchoring

SKU: 66445950271

4.8
USD141.00 USD190.00

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SMG9 Polyclonal Antibody, 100ul Isothermal Amplification Acts as a nucleolar anchoringThis gene encodes a regulatory subunit of the SMG1 complex, which plays a critical role in nonsense mediated mRNA decay (NMD). Binding of the encoded protein to the SMG1 complex kinase scaffold protein results in the inhibition of its kinase activity. Mutations in this gene cause a multiple congenital anomaly syndrome in human patients, characterized by brain malformation, congenital heart disease and other features.

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Description

Acts as a nucleolar anchoring protein for DDX47

which houses over 500 genes and is the second smallest human chromosome

which implicated the role of

Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1

Although its function is unknown| the observation that this gene is conserved in the mouse implies it has some function

SMG9 Polyclonal Antibody, 100ul Isothermal Amplification Acts as a nucleolar anchoringThis gene encodes a regulatory subunit of the SMG1 complex, which plays a critical role in nonsense mediated mRNA decay (NMD). Binding of the encoded protein to the SMG1 complex kinase scaffold protein results in the inhibition of its kinase activity. Mutations in this gene cause a multiple congenital anomaly syndrome in human patients, characterized by brain malformation, congenital heart disease and other features.

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