TFIIB Monoclonal Antibody, 100ul[BT-MCA1197] Contamination Detection & Removal The encoded protein was isolated

The encoded protein was isolated by virtue of its binding to an upstream element of the alpha2(I) collagen promoter

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Mutations in this gene have been associated with cardiac septal defects

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TFIIB Monoclonal Antibody, 100ul[BT-MCA1197] Contamination Detection & Removal The encoded protein was isolatedThis gene encodes the general transcription factor IIB, one of the ubiquitous factors required for transcription initiation by RNA polymerase II. The protein localizes to the nucleus where it forms a complex (the DAB complex) with transcription factors IID and IIA. Transcription factor IIB serves as a bridge between IID, the factor which initially recognizes the promoter sequence, and RNA polymerase II.