SPHK1 Polyclonal Antibody, 100ul Metabolic enzymes Ectonucleotide pyrophosphatase/phosphodiesterase family member 3

Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 encoded by ENPP3 belongs to a series of ectoenzymes that are involved in hydrolysis of extracellular nucleotides

This protein comprises an extracellular domain| an hydrophobic stretch corresponding to a single pass transmembrane region| and an intracellular kinase domain

The branched-chain alpha-ketoacid dehydrogenase complex (BCKD) is an important regulator of the valine

however| not all variants have been fully described

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SPHK1 Polyclonal Antibody, 100ul Metabolic enzymes Ectonucleotide pyrophosphatase/phosphodiesterase family member 3The protein encoded by this gene catalyzes the phosphorylation of sphingosine to form sphingosine 1 phosphate (S1P), a lipid mediator with both intra and extracellular functions. Intracellularly, S1P regulates proliferation and survival, and extracellularly, it is a ligand for cell surface G protein coupled receptors. This protein, and its product S1P, play a key role in TNF alpha signaling and the NF kappa B activation pathway important in